Tc1 Cells

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immunotherapy

Tc1 cells are type-1 cytotoxic CD8 T cells, characterized by IFN-γ and TNF-α production and the transcription factors T-bet and Eomes.

Source papers

  • Exercise-Induced Microbiota Metabolite Enhances CD8 T Cell Antitumor Immunity Promoting Immunotherapy Efficacy Catherine M. Phelps, Nathaniel B. Willis, Tingting Duan, et al., Giorgio Trinchieri, Marlies Meisel · 2025 doi:10.1016/j.cell.2025.06.018