drug-resistance
HDAC9 (Histone Deacetylase 9) is a class IIa histone deacetylase, an enzyme that removes acetyl groups from histone and non-histone substrates to regulate chromatin state and protein function. It is upregulated in various cancers and has been implicated in autophagy regulation and anticancer drug resistance, alongside established roles in other tissue contexts.
Related terms
Source papers
- HDAC9 and miR-512 Regulate CAGE-Promoted Anti-Cancer Drug Resistance and Cellular Proliferation doi:10.3390/cimb46060311